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Irisin reverses the IL-6 induced epithelial-mesenchymal transition in osteosarcoma cell migration and invasion through the STAT3/Snail signaling pathway

As a novel discovered myokine, irisin is considered to be a promising candidate for the treatment of metabolic disorders and cancer. However, little is known about the anti-metastasic effect of irisin on osteosarcoma cells and its underlying mechanisms. In the present study, we aimed to explore the...

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Detalles Bibliográficos
Autores principales: Kong, Gang, Jiang, Yunpeng, Sun, Xiujiang, Cao, Zhilin, Zhang, Guodong, Zhao, Zhongyuan, Zhao, Yong, Yu, Qian, Cheng, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780017/
https://www.ncbi.nlm.nih.gov/pubmed/29048621
http://dx.doi.org/10.3892/or.2017.5973