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SP1 promotes tumor angiogenesis and invasion by activating VEGF expression in an acquired trastuzumab-resistant ovarian cancer model

Ovarian cancer is one of the most common gynecologic cancers and the leading cause of mortality in women worldwide. HER2/neu is overexpressed in various types of cancers and is most commonly associated with decreased survival. Trastuzumab is a humanized anti-HER2 monoclonal antibody for the treatmen...

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Detalles Bibliográficos
Autores principales: Su, Feng, Geng, Jing, Li, Xinying, Qiao, Chuan, Luo, Longlong, Feng, Jiannan, Dong, Xinjun, Lv, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780020/
https://www.ncbi.nlm.nih.gov/pubmed/29048687
http://dx.doi.org/10.3892/or.2017.5998