VEGFR3 inhibition chemosensitizes lung adenocarcinoma A549 cells in the tumor-associated macrophage microenvironment through upregulation of p53 and PTEN

In lung adenocarcinoma, loss of p53 and PTEN in tumors are associated with decreased response to chemotherapy and decreased survival. A means to pharmacologically upregulate p53 and PTEN protein expression could improve the prognosis of patients with p53- and PTEN-deficient tumors. In the present st...

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Detalles Bibliográficos
Autores principales: Li, Ya, Weng, Yaguang, Zhong, Liang, Chong, Huimin, Chen, Sicheng, Sun, Yanting, Li, Wang, Shi, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780029/
https://www.ncbi.nlm.nih.gov/pubmed/29048623
http://dx.doi.org/10.3892/or.2017.5969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780029/
https://www.ncbi.nlm.nih.gov/pubmed/29048623
http://dx.doi.org/10.3892/or.2017.5969

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