High pemetrexed sensitivity of docetaxel-resistant A549 cells is mediated by TP53 status and downregulated thymidylate synthase

The chemoresistance of non-small cell lung cancer (NSCLC) that occurs in docetaxel (DOC) chemotherapy substantially decreases the survival of patients. To overcome DOC-induced chemoresistance, we established DOC-selected A549 lung cancer sublines (A549/D16 and A549/D32) and revealed that both sublin...

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Detalles Bibliográficos
Autores principales: Kuo, Wei-Ting, Tu, Dom-Gene, Chiu, Ling-Yen, Sheu, Gwo-Tarng, Wu, Ming-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780031/
https://www.ncbi.nlm.nih.gov/pubmed/28901493
http://dx.doi.org/10.3892/or.2017.5951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780031/
https://www.ncbi.nlm.nih.gov/pubmed/28901493
http://dx.doi.org/10.3892/or.2017.5951

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