Cargando…

Silencing of histone methyltransferase NSD3 reduces cell viability in osteosarcoma with induction of apoptosis

NSD3 is a histone lysine methyltransferase that methylates histone H3 at lysine 36. NSD3 is located at chromosome 8p11.23, the locus that exhibits strong cancer relevance. Thus, NSD3 is likely involved in multiple human cancers. Nevertheless, its roles in human carcinogenesis remain unknown. In the...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Zhiwei, Piao, Lianhua, Zhuang, Ming, Qiu, Xubin, Xu, Xiaoshuang, Zhang, Dawei, Liu, Mengmeng, Ren, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780032/
https://www.ncbi.nlm.nih.gov/pubmed/28901481
http://dx.doi.org/10.3892/or.2017.5936