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Paeoniflorin blocks the proliferation of vascular smooth muscle cells induced by platelet-derived growth factor-BB through ROS mediated ERK1/2 and p38 signaling pathways

The proliferation of vascular smooth muscle cells (VSMCs) contributes to the development of vascular remodeling. In the present study, the effect of paeoniflorin (PAE) on the platelet derived growth factor-BB (PDGF-BB)-induced proliferation of primary cultured rat VSMCs and its molecular mechanism w...

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Detalles Bibliográficos
Autores principales: Fan, Xianwei, Wu, Jintao, Yang, Haitao, Yan, Lijie, Wang, Shanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780110/
https://www.ncbi.nlm.nih.gov/pubmed/29257209
http://dx.doi.org/10.3892/mmr.2017.8093