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SUMO1/UBC9-decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy

Diabetic retinopathy (DR) is an increasing global health concern that causes vision loss and blindness. Reactive oxygen species (ROS) are considered to be a principal cause of DR. An important source of ROS is the oxidization of NADPH. In the present study, NADPH oxidase 1 (Nox1)-expressing human re...

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Detalles Bibliográficos
Autores principales: Hu, Jiaoli, Xue, Pengcheng, Mao, Xinbang, Xie, Lin, Li, Guodong, You, Zhipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780112/
https://www.ncbi.nlm.nih.gov/pubmed/29138839
http://dx.doi.org/10.3892/mmr.2017.8037