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Wnt/β-catenin pathway activation and silencing of the APC gene in HPV-positive human cervical cancer-derived cells

Although persistent infections with high-risk human papilloma virus (HPV) constitute the most significant cofactor for the development of cervical cancer, they are insufficient on their own. Mutations or epigenetic inactivation of the tumor suppressor adenomatous polyposis coli (APC), the two acting...

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Detalles Bibliográficos
Autores principales: Ayala-Calvillo, Erick, Mojica-Vázquez, Luis Humberto, García-Carrancá, Alejandro, González-Maya, Leticia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780127/
https://www.ncbi.nlm.nih.gov/pubmed/29115417
http://dx.doi.org/10.3892/mmr.2017.7853