TALENs-mediated homozygous CCR5Δ32 mutations endow CD4(+) U87 cells with resistance against HIV-1 infection

Since evidence suggests that transplantation of bone marrow stem cells with the C-C chemokine receptor type 5 (CCR5)Δ32/Δ32 genotype may cure patients infected with human immunodeficiency virus (HIV)-1, the present study aimed to reproduce the CCR5Δ32 mutation in cluster of differentiation (CD)4(+)...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Ai Qing, Ding, Yan, Lu, Zhi Yong, Hao, Yan Zhe, Teng, Zhi Ping, Yan, Shi Rong, Li, Dong Sheng, Zeng, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780131/
https://www.ncbi.nlm.nih.gov/pubmed/29115572
http://dx.doi.org/10.3892/mmr.2017.7889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780131/
https://www.ncbi.nlm.nih.gov/pubmed/29115572
http://dx.doi.org/10.3892/mmr.2017.7889

Ejemplares similares