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TALENs-mediated homozygous CCR5Δ32 mutations endow CD4(+) U87 cells with resistance against HIV-1 infection

Since evidence suggests that transplantation of bone marrow stem cells with the C-C chemokine receptor type 5 (CCR5)Δ32/Δ32 genotype may cure patients infected with human immunodeficiency virus (HIV)-1, the present study aimed to reproduce the CCR5Δ32 mutation in cluster of differentiation (CD)4(+)...

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Detalles Bibliográficos
Autores principales:	Yu, Ai Qing, Ding, Yan, Lu, Zhi Yong, Hao, Yan Zhe, Teng, Zhi Ping, Yan, Shi Rong, Li, Dong Sheng, Zeng, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780131/ https://www.ncbi.nlm.nih.gov/pubmed/29115572 http://dx.doi.org/10.3892/mmr.2017.7889

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