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TIPE2 governs macrophage polarization via negative regulation of mTORC1
Macrophages can be polarized into the inflammatory M1 lineage or the immunomodulatory M2 lineage, depending on the differential tissue microenvironment signaling, specific pathogens or cytokine stimulation. Tumor necrosis factor α-induced protein 8-like protein 2 (TIPE2) has been demonstrated to neg...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780176/ https://www.ncbi.nlm.nih.gov/pubmed/29115630 http://dx.doi.org/10.3892/mmr.2017.7991 |