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TIPE2 governs macrophage polarization via negative regulation of mTORC1

Macrophages can be polarized into the inflammatory M1 lineage or the immunomodulatory M2 lineage, depending on the differential tissue microenvironment signaling, specific pathogens or cytokine stimulation. Tumor necrosis factor α-induced protein 8-like protein 2 (TIPE2) has been demonstrated to neg...

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Detalles Bibliográficos
Autores principales: Jiang, Yuan, Li, Qiang, Zhang, Yuanyuan, Gao, Yuzhi, Jiang, Libing, Chen, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780176/
https://www.ncbi.nlm.nih.gov/pubmed/29115630
http://dx.doi.org/10.3892/mmr.2017.7991