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Carnosic Acid Alleviates BDL-Induced Liver Fibrosis through miR-29b-3p-Mediated Inhibition of the High-Mobility Group Box 1/Toll-Like Receptor 4 Signaling Pathway in Rats

Fibrosis reflects a progression to liver cancer or cirrhosis of the liver. Recent studies have shown that high-mobility group box-1 (HMGB1) plays a major role in hepatic injury and fibrosis. Carnosic acid (CA), a compound extracted from rosemary, has been reported to alleviate alcoholic and non-alco...

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Detalles Bibliográficos
Autores principales: Zhang, Shuai, Wang, Zhecheng, Zhu, Jie, Xu, Ting, Zhao, Yan, Zhao, Huanyu, Tang, Fan, Li, Zhenlu, Zhou, Junjun, Gao, Dongyan, Tian, Xiaofeng, Yao, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780338/
https://www.ncbi.nlm.nih.gov/pubmed/29403377
http://dx.doi.org/10.3389/fphar.2017.00976