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Alzheimer’s Disease Mutant Mice Exhibit Reduced Brain Tissue Stiffness Compared to Wild-type Mice in both Normoxia and following Intermittent Hypoxia Mimicking Sleep Apnea

BACKGROUND: Evidence from patients and animal models suggests that obstructive sleep apnea (OSA) may increase the risk of Alzheimer’s disease (AD) and that AD is associated with reduced brain tissue stiffness. AIM: To investigate whether intermittent hypoxia (IH) alters brain cortex tissue stiffness...

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Detalles Bibliográficos
Autores principales: Menal, Maria José, Jorba, Ignasi, Torres, Marta, Montserrat, Josep M., Gozal, David, Colell, Anna, Piñol-Ripoll, Gerard, Navajas, Daniel, Almendros, Isaac, Farré, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780342/
https://www.ncbi.nlm.nih.gov/pubmed/29403429
http://dx.doi.org/10.3389/fneur.2018.00001