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Alzheimer’s Disease Mutant Mice Exhibit Reduced Brain Tissue Stiffness Compared to Wild-type Mice in both Normoxia and following Intermittent Hypoxia Mimicking Sleep Apnea
BACKGROUND: Evidence from patients and animal models suggests that obstructive sleep apnea (OSA) may increase the risk of Alzheimer’s disease (AD) and that AD is associated with reduced brain tissue stiffness. AIM: To investigate whether intermittent hypoxia (IH) alters brain cortex tissue stiffness...
Autores principales: | Menal, Maria José, Jorba, Ignasi, Torres, Marta, Montserrat, Josep M., Gozal, David, Colell, Anna, Piñol-Ripoll, Gerard, Navajas, Daniel, Almendros, Isaac, Farré, Ramon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780342/ https://www.ncbi.nlm.nih.gov/pubmed/29403429 http://dx.doi.org/10.3389/fneur.2018.00001 |
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