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Pretreatment with AQP4 and NKCC1 Inhibitors Concurrently Attenuated Spinal Cord Edema and Tissue Damage after Spinal Cord Injury in Rats

Spinal cord injury (SCI) affects more than 2.5 million people worldwide. Spinal cord edema plays critical roles in the pathological progression of SCI. This study aimed to delineate the roles of aquaporin 4 (AQP4) and Na(+)-K(+)-Cl(−) cotransporter 1 (NKCC1) in acute phase edema and tissue destructi...

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Detalles Bibliográficos
Autores principales: Yan, Xiaodong, Liu, Juanfang, Wang, Xiji, Li, Wenhao, Chen, Jingyuan, Sun, Honghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780344/
https://www.ncbi.nlm.nih.gov/pubmed/29403391
http://dx.doi.org/10.3389/fphys.2018.00006