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Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes

The reversible modification of cysteine residues by thioester formation with palmitate (S-palmitoylation) is an abundant lipid post-translational modification (PTM) in mammalian systems. S-palmitoylation has been observed on mitochondrial proteins, providing an intriguing potential connection betwee...

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Detalles Bibliográficos
Autores principales: Kathayat, Rahul S., Cao, Yang, Elvira, Pablo D., Sandoz, Patrick A., Zaballa, María-Eugenia, Springer, Maya Z., Drake, Lauren E., Macleod, Kay F., van der Goot, F. Gisou, Dickinson, Bryan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780395/
https://www.ncbi.nlm.nih.gov/pubmed/29362370
http://dx.doi.org/10.1038/s41467-017-02655-1