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Real-Time Quaking-Induced Conversion Detection of Bovine Spongiform Encephalopathy Prions in a Subclinical Steer

Bovine spongiform encephalopathy (BSE) belongs to a group of fatal prion diseases that result from the misfolding of the cellular prion protein (PrP(C)) into a pathogenic form (PrP(Sc)) that accumulates in the brain. In vitro assays such as serial protein misfolding amplification and real-time quaki...

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Detalles Bibliográficos
Autores principales: Hwang, Soyoun, West Greenlee, M. Heather, Balkema-Buschmann, Anne, Groschup, Martin H., Nicholson, Eric M., Greenlee, Justin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780402/
https://www.ncbi.nlm.nih.gov/pubmed/29404344
http://dx.doi.org/10.3389/fvets.2017.00242