Absence of Tumor Necrosis Factor Supports Alternative Activation of Macrophages in the Liver after Infection with Leishmania major

The absence of tumor necrosis factor (TNF) causes lethal infection by Leishmania major in normally resistant C57BL/6J (B6.WT) mice. The underlying pathogenic mechanism of this fatal disease has so far remained elusive. We found that B6.WT mice deficient for the tnf gene (B6.TNF(−/−)) displayed not o...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Shanshan, Marshall, Cameron, Darby, Jocelyn, Wei, Wei, Lyons, Alan Bruce, Körner, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780437/
https://www.ncbi.nlm.nih.gov/pubmed/29403488
http://dx.doi.org/10.3389/fimmu.2018.00001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780437/
https://www.ncbi.nlm.nih.gov/pubmed/29403488
http://dx.doi.org/10.3389/fimmu.2018.00001

Ejemplares similares