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Lethal mutagenesis of an RNA plant virus via lethal defection

Lethal mutagenesis is an antiviral therapy that relies on increasing the viral mutation rate with mutagenic nucleoside or base analogues. Currently, the molecular mechanisms that lead to virus extinction through enhanced mutagenesis are not fully understood. Increasing experimental evidence supports...

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Detalles Bibliográficos
Autores principales: Díaz-Martínez, Luis, Brichette-Mieg, Isabel, Pineño-Ramos, Axier, Domínguez-Huerta, Guillermo, Grande-Pérez, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780445/
https://www.ncbi.nlm.nih.gov/pubmed/29362502
http://dx.doi.org/10.1038/s41598-018-19829-6