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Lethal mutagenesis of an RNA plant virus via lethal defection
Lethal mutagenesis is an antiviral therapy that relies on increasing the viral mutation rate with mutagenic nucleoside or base analogues. Currently, the molecular mechanisms that lead to virus extinction through enhanced mutagenesis are not fully understood. Increasing experimental evidence supports...
Autores principales: | Díaz-Martínez, Luis, Brichette-Mieg, Isabel, Pineño-Ramos, Axier, Domínguez-Huerta, Guillermo, Grande-Pérez, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780445/ https://www.ncbi.nlm.nih.gov/pubmed/29362502 http://dx.doi.org/10.1038/s41598-018-19829-6 |
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