Controlling AOX1 promoter strength in Pichia pastoris by manipulating poly (dA:dT) tracts

Alcohol oxidase I (AOX1) promoter is the most popular but strictly-regulated methanol inducible promoter for heterologous protein expression in Pichia pastoris. In recent years, AOX1 promoter libraries have been developed with deletion or insertion methods. The present research manipulated poly (dA:...

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Detalles Bibliográficos
Autores principales: Yang, Jun, Cai, Haiming, Liu, Jie, Zeng, Min, Chen, Jiawei, Cheng, Qingmei, Zhang, Linghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780452/
https://www.ncbi.nlm.nih.gov/pubmed/29362428
http://dx.doi.org/10.1038/s41598-018-19831-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780452/
https://www.ncbi.nlm.nih.gov/pubmed/29362428
http://dx.doi.org/10.1038/s41598-018-19831-y

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