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Controlling AOX1 promoter strength in Pichia pastoris by manipulating poly (dA:dT) tracts
Alcohol oxidase I (AOX1) promoter is the most popular but strictly-regulated methanol inducible promoter for heterologous protein expression in Pichia pastoris. In recent years, AOX1 promoter libraries have been developed with deletion or insertion methods. The present research manipulated poly (dA:...
Autores principales: | Yang, Jun, Cai, Haiming, Liu, Jie, Zeng, Min, Chen, Jiawei, Cheng, Qingmei, Zhang, Linghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780452/ https://www.ncbi.nlm.nih.gov/pubmed/29362428 http://dx.doi.org/10.1038/s41598-018-19831-y |
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