Efficient inhibition of African swine fever virus replication by CRISPR/Cas9 targeting of the viral p30 gene (CP204L)

African swine fever is a devastating viral disease of domestic and wild pigs against which no vaccine or therapy is available. Therefore, we applied the CRISPR (clustered regularly interspaced short palindromic repeats) – Cas9 nuclease system to target the double-stranded DNA genome of African swine...

Descripción completa

Detalles Bibliográficos
Autores principales: Hübner, Alexandra, Petersen, Bjoern, Keil, Günther M., Niemann, Heiner, Mettenleiter, Thomas C., Fuchs, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780455/
https://www.ncbi.nlm.nih.gov/pubmed/29362418
http://dx.doi.org/10.1038/s41598-018-19626-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780455/
https://www.ncbi.nlm.nih.gov/pubmed/29362418
http://dx.doi.org/10.1038/s41598-018-19626-1

Ejemplares similares