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Efficient inhibition of African swine fever virus replication by CRISPR/Cas9 targeting of the viral p30 gene (CP204L)

African swine fever is a devastating viral disease of domestic and wild pigs against which no vaccine or therapy is available. Therefore, we applied the CRISPR (clustered regularly interspaced short palindromic repeats) – Cas9 nuclease system to target the double-stranded DNA genome of African swine...

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Detalles Bibliográficos
Autores principales:	Hübner, Alexandra, Petersen, Bjoern, Keil, Günther M., Niemann, Heiner, Mettenleiter, Thomas C., Fuchs, Walter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780455/ https://www.ncbi.nlm.nih.gov/pubmed/29362418 http://dx.doi.org/10.1038/s41598-018-19626-1

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