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Sequential transfection of RUNX2/SP7 and ATF4 coated onto dexamethasone-loaded nanospheres enhances osteogenesis

The timing of gene transfection greatly influences stem cell differentiation. Sequential transfection is crucial for regulation of cell behavior. When transfected several days after differentiation initiation, genes expressed at the late stage of differentiation can regulate cell behaviors and funct...

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Detalles Bibliográficos
Autores principales: Kim, Hye Jin, Park, Ji Sun, Yi, Se Won, Oh, Hyun Jyung, Kim, Jae-Hwan, Park, Keun-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780485/
https://www.ncbi.nlm.nih.gov/pubmed/29362501
http://dx.doi.org/10.1038/s41598-018-19824-x