Deletion of DGCR8 in VSMCs of adult mice results in loss of vascular reactivity, reduced blood pressure and neointima formation

DiGeorge syndrome chromosomal region 8 (DGCR8), a double-stranded-RNA-binding protein, participates in the miRNA biogenesis pathway and contributes to miRNA maturation by interacting with the RNAase III enzyme Drosha in cell nuclei. To investigate the role of DGCR8 in vascular smooth muscle cells (V...

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Detalles Bibliográficos
Autores principales: Zou, Yanan, Chen, Zixuan, Jennings, Brett L., Zhao, Guannan, Gu, Qingqing, Bhattacharya, Anindya, Cui, Yan, Yu, Bo, Malik, Kafait U., Yue, Junming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780492/
https://www.ncbi.nlm.nih.gov/pubmed/29362439
http://dx.doi.org/10.1038/s41598-018-19660-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780492/
https://www.ncbi.nlm.nih.gov/pubmed/29362439
http://dx.doi.org/10.1038/s41598-018-19660-z

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