The intronic G13964C variant in p53 is not a high-risk mutation in familial breast cancer in Australia

BACKGROUND: Mutations in BRCA1 and BRCA2 account for approximately 50% of breast cancer families with more than four affected cases, whereas exonic mutations in p53, PTEN, CHK2 and ATM may account for a very small proportion. It was recently reported that an intronic variant of p53 - G13964C - occur...

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Detalles Bibliográficos
Autores principales: Marsh, Anna, Spurdle, Amanda B, Turner, Bruce C, Fereday, Sian, Thorne, Heather, Pupo, Gulietta M, Mann, Graham J, Hopper, John L, Sambrook, Joseph F, Chenevix-Trench, Georgia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC57805/
https://www.ncbi.nlm.nih.gov/pubmed/11597326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC57805/
https://www.ncbi.nlm.nih.gov/pubmed/11597326

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