Insights into the molecular mechanism of dehalogenation catalyzed by D-2-haloacid dehalogenase from crystal structures

D-2-haloacid dehalogenases (D-DEXs) catalyse the hydrolytic dehalogenation of D-2-haloacids, releasing halide ions and producing the corresponding 2-hydroxyacids. A structure-guided elucidation of the catalytic mechanism of this dehalogenation reaction has not been reported yet. Here, we report the...

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Detalles Bibliográficos
Autores principales: Wang, Yayue, Feng, Yanbin, Cao, Xupeng, Liu, Yinghui, Xue, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780510/
https://www.ncbi.nlm.nih.gov/pubmed/29362453
http://dx.doi.org/10.1038/s41598-017-19050-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780510/
https://www.ncbi.nlm.nih.gov/pubmed/29362453
http://dx.doi.org/10.1038/s41598-017-19050-x

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