Cargando…

Insights into the molecular mechanism of dehalogenation catalyzed by D-2-haloacid dehalogenase from crystal structures

D-2-haloacid dehalogenases (D-DEXs) catalyse the hydrolytic dehalogenation of D-2-haloacids, releasing halide ions and producing the corresponding 2-hydroxyacids. A structure-guided elucidation of the catalytic mechanism of this dehalogenation reaction has not been reported yet. Here, we report the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yayue, Feng, Yanbin, Cao, Xupeng, Liu, Yinghui, Xue, Song
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780510/ https://www.ncbi.nlm.nih.gov/pubmed/29362453 http://dx.doi.org/10.1038/s41598-017-19050-x

Ejemplares similares

Mini Review: Advances in 2-Haloacid Dehalogenases
por: Wang, Yayue, et al.
Publicado: (2021)

Haloacid Dehalogenase Proteins: Novel Mediators of Metabolic Plasticity in Plasmodium falciparum
por: Frasse, Philip M, et al.
Publicado: (2019)

The conserved crown bridge loop at the catalytic centre of enzymes of the haloacid dehalogenase superfamily
por: Leader, David P., et al.
Publicado: (2023)

Dehalogenases: From Improved Performance to Potential Microbial Dehalogenation Applications
por: Ang, Thiau-Fu, et al.
Publicado: (2018)

Reductive dehalogenase structure suggests a mechanism for B12-dependent dehalogenation
por: Payne, Karl AP, et al.
Publicado: (2014)

l-2-Haloacid dehalogenase (DehL) from Rhizobium sp. RC1
por: Adamu, Aliyu, et al.
Publicado: (2016)

Genome-wide analysis of haloacid dehalogenase genes reveals their function in phosphate starvation responses in rice
por: Du, Zezhen, et al.
Publicado: (2021)

Efficient NADPH-dependent dehalogenation afforded by a self-sufficient reductive dehalogenase
por: Fisher, Karl, et al.
Publicado: (2023)

Optimization of haloacid dehalogenase production by recombinant E. coli BL21 (DE3)/pET-hakp1 containing haloacid dehalogenase gene from Klebsiella pneumoniae ITB1 using Response Surface Methodology (RSM)
por: Ratnaningsih, Enny, et al.
Publicado: (2022)

X‐ray structure and mechanism of ZgHAD, a l‐2‐haloacid dehalogenase from the marine Flavobacterium Zobellia galactanivorans
por: Grigorian, Eugénie, et al.
Publicado: (2023)

In-silico gene co-expression network analysis in Paracoccidioides brasiliensis with reference to haloacid dehalogenase superfamily hydrolase gene
por: Satpathy, Raghunath, et al.
Publicado: (2015)

In Silico Analysis on the Interaction of Haloacid Dehalogenase from Bacillus cereus IndB1 with 2-Chloroalkanoic Acid Substrates
por: Ratnaningsih, Enny, et al.
Publicado: (2022)

Oxidative dehalogenation of trichlorophenol catalyzed by a promiscuous artificial heme-enzyme
por: Zambrano, Gerardo, et al.
Publicado: (2022)

Functional Characterization of a L-2-Haloacid Dehalogenase From Zobellia galactanivorans Dsij(T) Suggests a Role in Haloacetic Acid Catabolism and a Wide Distribution in Marine Environments
por: Grigorian, Eugénie, et al.
Publicado: (2021)

Yihx-encoded haloacid dehalogenase-like phosphatase HAD4 from Escherichia coli is a specific α-d-glucose 1-phosphate hydrolase useful for substrate-selective sugar phosphate transformations
por: Pfeiffer, Martin, et al.
Publicado: (2014)

Dual Element (C/Cl) Isotope Analysis Indicates Distinct Mechanisms of Reductive Dehalogenation of Chlorinated Ethenes and Dichloroethane in Dehalococcoides mccartyi Strain BTF08 With Defined Reductive Dehalogenase Inventories
por: Franke, Steffi, et al.
Publicado: (2020)

Enantioselective photoredox dehalogenative protonation
por: Hou, Meimei, et al.
Publicado: (2019)

Film formation from plasma-enabled surface-catalyzed dehalogenative coupling of a small organic molecule
por: Hartl, Hugo, et al.
Publicado: (2019)

Reductive dehalogenation of bromoform in aqueous solution.
por: Betterton, E A, et al.
Publicado: (1995)

Draft Genome Sequence of the Haloacid-Degrading Burkholderia caribensis Strain MBA4
por: Pan, Yanling, et al.
Publicado: (2014)

Complete genome sequence and characterization of the haloacid–degrading Burkholderia caribensis MBA4
por: Pan, Yanling, et al.
Publicado: (2015)

G‐type Halohydrin Dehalogenases Catalyze Ring Opening Reactions of Cyclic Epoxides with Diverse Anionic Nucleophiles
por: Solarczek, Jennifer, et al.
Publicado: (2022)

An Ultrasensitive Fluorescence Assay for the Detection of Halides and Enzymatic Dehalogenation
por: Aslan‐Üzel, Aşkın S., et al.
Publicado: (2020)

Dehalogenation reactions between halide salts and phosphate compounds
por: Riley, Brian J., et al.
Publicado: (2022)

Insights into the stereospecificity of the d-specific dehalogenase from Rhizobium sp. RC1 toward d- and l-2-chloropropionate
por: Sudi, Ismaila Yada, et al.
Publicado: (2014)

Presence, Diversity, and Enrichment of Respiratory Reductive Dehalogenase and Non-respiratory Hydrolytic and Oxidative Dehalogenase Genes in Terrestrial Environments
por: Temme, Hanna R., et al.
Publicado: (2019)

Kinetics and Mechanism of Plasmon-Driven Dehalogenation Reaction of Brominated Purine Nucleobases on Ag and Au
por: Dutta, Anushree, et al.
Publicado: (2021)

A Catalytic Borylation/Dehalogenation Route to o-Fluoro Arylboronates
por: Jayasundara, Chathurika R. K., et al.
Publicado: (2014)

Efficient Indium-Mediated Dehalogenation of Aromatics in Ionic Liquid Media
por: Cañete, Álvaro F., et al.
Publicado: (2012)

Phosphonic acid mediated practical dehalogenation and benzylation with benzyl halides
por: Xiao, Jing, et al.
Publicado: (2019)

Oxy‐Borylenes as Photoreductants: Synthesis and Application in Dehalogenation and Detosylation Reactions
por: Lenz, Philipp, et al.
Publicado: (2022)

Asymmetric Synthesis of 4,1-Benzoxazepine-2,5-Diones — Effect of the Halogen of (2S)-α-Haloacids
por: Rubab, Syeda Laila, et al.
Publicado: (2013)

Application of qPCR assays based on haloacids transporter gene dehp2 for discrimination of Burkholderia and Paraburkholderia
por: Su, Xianbin, et al.
Publicado: (2019)

Rapid Kinetics of Dehalogenation Promoted by Iodotyrosine Deiodinase from Human Thyroid
por: Bobyk, Kostyantyn D., et al.
Publicado: (2015)

Original Synthesis of Fluorenyl Alcohol Derivatives by Reductive Dehalogenation Initiated by TDAE
por: Giuglio-Tonolo, Alain Gamal, et al.
Publicado: (2016)

Fungal Strains as Catalysts for the Biotransformation of Halolactones by Hydrolytic Dehalogenation with the Dimethylcyclohexane System
por: Grabarczyk, Małgorzata
Publicado: (2012)

Targeted radionuclide therapy with astatine-211: Oxidative dehalogenation of astatobenzoate conjugates
por: Teze, David, et al.
Publicado: (2017)

Genomic and Transcriptomic Analysis of Growth-Supporting Dehalogenation of Chlorinated Methanes in Methylobacterium
por: Chaignaud, Pauline, et al.
Publicado: (2017)

Structure Prediction, Molecular Dynamics Simulation and Docking Studies of D-Specific Dehalogenase from Rhizobium sp. RC1
por: Sudi, Ismaila Yada, et al.
Publicado: (2012)

Guided cobamide biosynthesis for heterologous production of reductive dehalogenases
por: Schubert, Torsten, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_hr265j5h1n0c23b8nj0uml1vug