Premature polyadenylation of MAGI3 is associated with diminished N(6)-methyladenosine in its large internal exon

In cancer, tumor suppressor genes (TSGs) are frequently truncated, causing their encoded products to be non-functional or dominant-negative. We previously showed that premature polyadenylation (pPA) of MAGI3 truncates the gene, switching its functional role from a TSG to a dominant-negative oncogene...

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Detalles Bibliográficos
Autores principales: Ni, Thomas K., Elman, Jessica S., Jin, Dexter X., Gupta, Piyush B., Kuperwasser, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780518/
https://www.ncbi.nlm.nih.gov/pubmed/29362392
http://dx.doi.org/10.1038/s41598-018-19916-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780518/
https://www.ncbi.nlm.nih.gov/pubmed/29362392
http://dx.doi.org/10.1038/s41598-018-19916-8

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