Cargando…
Premature polyadenylation of MAGI3 is associated with diminished N(6)-methyladenosine in its large internal exon
In cancer, tumor suppressor genes (TSGs) are frequently truncated, causing their encoded products to be non-functional or dominant-negative. We previously showed that premature polyadenylation (pPA) of MAGI3 truncates the gene, switching its functional role from a TSG to a dominant-negative oncogene...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780518/ https://www.ncbi.nlm.nih.gov/pubmed/29362392 http://dx.doi.org/10.1038/s41598-018-19916-8 |