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Immune Tolerance to Apoptotic Self Is Mediated Primarily by Regulatory B1a Cells
The chronic autoimmune inflammatory diseases, systemic lupus erythematosus and Sjogren’s syndrome, develop when tolerance to apoptotic cells (ACs) is lost. We have previously reported that this tolerance is maintained by innate-like, IL-10 secreting regulatory B cells. Two questions remained. First,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780629/ https://www.ncbi.nlm.nih.gov/pubmed/29403471 http://dx.doi.org/10.3389/fimmu.2017.01952 |