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Immune Tolerance to Apoptotic Self Is Mediated Primarily by Regulatory B1a Cells

The chronic autoimmune inflammatory diseases, systemic lupus erythematosus and Sjogren’s syndrome, develop when tolerance to apoptotic cells (ACs) is lost. We have previously reported that this tolerance is maintained by innate-like, IL-10 secreting regulatory B cells. Two questions remained. First,...

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Detalles Bibliográficos
Autores principales: Miles, Katherine, Simpson, Joanne, Brown, Sheila, Cowan, Graeme, Gray, David, Gray, Mohini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780629/
https://www.ncbi.nlm.nih.gov/pubmed/29403471
http://dx.doi.org/10.3389/fimmu.2017.01952