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Thrombopoietin protects H9C2 cells from excessive autophagy and apoptosis in doxorubicin-induced cardiotoxicity

Cardiac toxicity has been the major concern when using doxorubicin (DOX) in cancer therapy. Thrombopoietin (TPO) protects cardiac cells from DOX-induced cell damage; however, its molecular mechanism remains exclusive. The anti-autophagic and anti-apoptotic effects of TPO upon DOX treatment were stud...

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Detalles Bibliográficos
Autores principales: Wang, Han, Wang, Hua, Liang, En-Yu, Zhou, Li-Xia, Dong, Zhan-Ling, Liang, Ping, Weng, Qi-Fang, Yang, Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780751/
https://www.ncbi.nlm.nih.gov/pubmed/29403560
http://dx.doi.org/10.3892/ol.2017.7410