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Thrombopoietin protects H9C2 cells from excessive autophagy and apoptosis in doxorubicin-induced cardiotoxicity
Cardiac toxicity has been the major concern when using doxorubicin (DOX) in cancer therapy. Thrombopoietin (TPO) protects cardiac cells from DOX-induced cell damage; however, its molecular mechanism remains exclusive. The anti-autophagic and anti-apoptotic effects of TPO upon DOX treatment were stud...
Autores principales: | Wang, Han, Wang, Hua, Liang, En-Yu, Zhou, Li-Xia, Dong, Zhan-Ling, Liang, Ping, Weng, Qi-Fang, Yang, Mo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780751/ https://www.ncbi.nlm.nih.gov/pubmed/29403560 http://dx.doi.org/10.3892/ol.2017.7410 |
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