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Discovery of cell-type specific DNA motif grammar in cis-regulatory elements using random Forest
BACKGROUND: It has been observed that many transcription factors (TFs) can bind to different genomic loci depending on the cell type in which a TF is expressed in, even though the individual TF usually binds to the same core motif in different cell types. How a TF can bind to the genome in such a hi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780765/ https://www.ncbi.nlm.nih.gov/pubmed/29363433 http://dx.doi.org/10.1186/s12864-017-4340-z |