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Structural Mechanisms of Gating in Ionotropic Glutamate Receptors

[Image: see text] Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that mediate the majority of excitatory neurotransmission in the central nervous system. iGluRs open their ion channels in response to binding of the neurotransmitter glutamate, rapidly depolarize the postsynapti...

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Detalles Bibliográficos
Autores principales: Twomey, Edward C., Sobolevsky, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780838/
https://www.ncbi.nlm.nih.gov/pubmed/29037031
http://dx.doi.org/10.1021/acs.biochem.7b00891