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A novel algorithm for finding optimal driver nodes to target control complex networks and its applications for drug targets identification

BACKGROUND: The advances in target control of complex networks not only can offer new insights into the general control dynamics of complex systems, but also be useful for the practical application in systems biology, such as discovering new therapeutic targets for disease intervention. In many case...

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Detalles Bibliográficos
Autores principales: Guo, Wei-Feng, Zhang, Shao-Wu, Shi, Qian-Qian, Zhang, Cheng-Ming, Zeng, Tao, Chen, Luonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780855/
https://www.ncbi.nlm.nih.gov/pubmed/29363426
http://dx.doi.org/10.1186/s12864-017-4332-z