Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1

BACKGROUND: Pancreatic progenitors (PPs) co-expressing the two transcription factors (TFs) PDX1 and NKX6.1 are recognized as the indispensable precursors of functional pancreatic β cells. Here, we aimed to establish an efficient protocol for maximizing generation of PDX1(+)/NKX6.1(+) PPs from human...

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Detalles Bibliográficos
Autores principales: Memon, Bushra, Karam, Manale, Al-Khawaga, Sara, Abdelalim, Essam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781269/
https://www.ncbi.nlm.nih.gov/pubmed/29361979
http://dx.doi.org/10.1186/s13287-017-0759-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781269/
https://www.ncbi.nlm.nih.gov/pubmed/29361979
http://dx.doi.org/10.1186/s13287-017-0759-z

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