IL-1β mediates lung neutrophilia and IL-33 expression in a mouse model of viral-induced asthma exacerbation

BACKGROUND: Viral-induced asthma exacerbations, which exhibit both Th1-type neutrophilia and Th2-type inflammation, associate with secretion of Interleukin (IL)-1β. IL-1β induces neutrophilic inflammation. It may also increase Th2-type cytokine expression. We hypothesised that IL-1β is causally invo...

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Detalles Bibliográficos
Autores principales: Mahmutovic Persson, Irma, Menzel, Mandy, Ramu, Sangeetha, Cerps, Samuel, Akbarshahi, Hamid, Uller, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781288/
https://www.ncbi.nlm.nih.gov/pubmed/29361942
http://dx.doi.org/10.1186/s12931-018-0725-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781288/
https://www.ncbi.nlm.nih.gov/pubmed/29361942
http://dx.doi.org/10.1186/s12931-018-0725-z

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