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Identification of reliable biomarkers of human papillomavirus 16 methylation in cervical lesions based on integration status using high-resolution melting analysis

BACKGROUND: The dynamic methylation of human papillomavirus (HPV) 16 DNA is thought to be associated with the progression of cervical lesions. Previous studies that did not consider the physical status of HPV 16 may have incorrectly mapped HPV 16 methylomes. In order to identify reliable biomarkers...

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Detalles Bibliográficos
Autores principales: Liu, Lu, Ying, Chunmei, Zhao, Zhen, Sui, Long, Zhang, Xinyan, Qian, Chunyan, Wang, Qing, Chen, Limei, Guo, Qisang, Wu, Jiangnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781301/
https://www.ncbi.nlm.nih.gov/pubmed/29410710
http://dx.doi.org/10.1186/s13148-018-0445-8