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A surrogate-based approach for post-genomic partner identification

BACKGROUND: Modern drug discovery is concerned with identification and validation of novel protein targets from among the 30,000 genes or more postulated to be present in the human genome. While protein-protein interactions may be central to many disease indications, it has been difficult to identif...

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Detalles Bibliográficos
Autores principales: Pillutla, Renuka C, Hsiao, Ku-chuan, Brissette, Renee, Eder, Paul S, Giordano, Tony, Fletcher, Paul W, Lennick, Michael, Blume, Arthur J, Goldstein, Neil I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC57814/
https://www.ncbi.nlm.nih.gov/pubmed/11602024
http://dx.doi.org/10.1186/1472-6750-1-6