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MIR-708 promotes phagocytosis to eradicate T-ALL cells by targeting CD47

Immunoevasion is a hallmark of cancer progression, and immune checkpoint blockade has emerged as a promising strategy for cancer treatment. microRNAs (miRNAs) are important negative regulators of gene expression in the immune system. Here, we demonstrate that miR-708 regulates CD47, a transmembrane...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Wang, Wen-Tao, Fang, Ke, Chen, Zhen-Hua, Sun, Yu-Meng, Han, Cai, Sun, Lin-Yu, Luo, Xue-Qun, Chen, Yue-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782377/
https://www.ncbi.nlm.nih.gov/pubmed/29368647
http://dx.doi.org/10.1186/s12943-018-0768-2