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Genomic 5-mC contents in peripheral blood leukocytes were independent protective factors for coronary artery disease with a specific profile in different leukocyte subtypes

BACKGROUND: Alterations in DNA methylation are demonstrated in atherosclerosis pathogenesis. However, changing rules of global DNA methylation and hydroxymethylation in peripheral blood leukocytes (PBLs) and different blood cell subtypes of coronary artery disease (CAD) patients are still inconclusi...

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Detalles Bibliográficos
Autores principales: Deng, Qianyun, Huang, Wei, Peng, Chunyan, Gao, Jiajia, Li, Zuhua, Qiu, Xueping, Yang, Na, Yuan, Bifeng, Zheng, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782379/
https://www.ncbi.nlm.nih.gov/pubmed/29410709
http://dx.doi.org/10.1186/s13148-018-0443-x