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Considerations for skin carcinogenesis experiments using inducible transgenic mouse models

OBJECTIVE: This study was designed to estimate the percentage of non-malignant skin tumours (papillomas) progressing to malignant squamous cell carcinomas (SCCs) in a carcinogenesis study using established transgenic mouse models. In our skin cancer model, we conditionally induced oncogenic point mu...

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Detalles Bibliográficos
Autores principales: Popis, Martyna C., Wagner, Rebecca E., Constantino-Casas, Fernando, Blanco, Sandra, Frye, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782388/
https://www.ncbi.nlm.nih.gov/pubmed/29361972
http://dx.doi.org/10.1186/s13104-018-3182-3