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An obesity-associated gut microbiome reprograms the intestinal epigenome and leads to altered colonic gene expression
BACKGROUND: The gut microbiome, a key constituent of the colonic environment, has been implicated as an important modulator of human health. The eukaryotic epigenome is postulated to respond to environmental stimuli through alterations in chromatin features and, ultimately, gene expression. How the...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782396/ https://www.ncbi.nlm.nih.gov/pubmed/29361968 http://dx.doi.org/10.1186/s13059-018-1389-1 |