An obesity-associated gut microbiome reprograms the intestinal epigenome and leads to altered colonic gene expression

BACKGROUND: The gut microbiome, a key constituent of the colonic environment, has been implicated as an important modulator of human health. The eukaryotic epigenome is postulated to respond to environmental stimuli through alterations in chromatin features and, ultimately, gene expression. How the...

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Detalles Bibliográficos
Autores principales: Qin, Yufeng, Roberts, John D., Grimm, Sara A., Lih, Fred B., Deterding, Leesa J., Li, Ruifang, Chrysovergis, Kaliopi, Wade, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782396/
https://www.ncbi.nlm.nih.gov/pubmed/29361968
http://dx.doi.org/10.1186/s13059-018-1389-1

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