Cargando…

The relationship between the PD-1/PD-L1 pathway and DNA mismatch repair in cervical cancer and its clinical significance

BACKGROUND: According to recent clinical observations, deficient DNA mismatch repair (dMMR) is capable of improving antitumor effects of the PD-1/PD-L1 pathway, suggesting that dMMR may act as a prognostic indicator of PD-1/PD-L1 antibody drugs. In this study, we examined the dMMR and PD-1/PD-L1 exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Feng, Yang-chun, Ji, Wen-li, Yue, Na, Huang, Yan-chun, Ma, Xiu-min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783151/
https://www.ncbi.nlm.nih.gov/pubmed/29403308
http://dx.doi.org/10.2147/CMAR.S152232