Anti-factor H antibody affecting factor H cofactor activity in a patient with dense deposit disease

Complement alternative pathway dysregulation seems to be the pathophysiological basis of Dense Deposit Disease (DDD). Here, we describe a monoclonal anti-factor H (FH) autoantibody in a woman diagnosed with DDD with a monoclonal gammapathy. Enzyme-linked immunosorbent assays evidenced the presence o...

Descripción completa

Detalles Bibliográficos
Autores principales: Nozal, Pilar, Strobel, Stefanie, Ibernon, Meritxell, López, Dolores, Sánchez-Corral, Pilar, Rodríguez de Córdoba, Santiago, Józsi, Mihály, López-Trascasa, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Original Contributions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783207/
https://www.ncbi.nlm.nih.gov/pubmed/29497514
http://dx.doi.org/10.1093/ckj/sfs002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783207/
https://www.ncbi.nlm.nih.gov/pubmed/29497514
http://dx.doi.org/10.1093/ckj/sfs002

Ejemplares similares