Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons

Chloride ions play an important role in controlling excitability of principal neurons in the central nervous system. When neurotransmitter GABA is released from inhibitory interneurons, activated GABA type A (GABA(A)) receptors on principal neurons become permeable to chloride. Typically, chloride f...

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Detalles Bibliográficos
Autores principales: Sørensen, Andreas T., Ledri, Marco, Melis, Miriam, Nikitidou Ledri, Litsa, Andersson, My, Kokaia, Merab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783240/
https://www.ncbi.nlm.nih.gov/pubmed/29379872
http://dx.doi.org/10.1523/ENEURO.0172-17.2017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783240/
https://www.ncbi.nlm.nih.gov/pubmed/29379872
http://dx.doi.org/10.1523/ENEURO.0172-17.2017

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